Design and Activity of a Murine and Humanized Anti-CEACAM6 Single-Chain Variable Fragment in the Treatment of Pancreatic Cancer.

Christopher J. Riley, Kevin P. Engelhardt,1 Jose W. Saldanha, Wenqing Qi, Laurence S. Cooke, Yingting Zhu, Satya T. Narayan, Kishore Shakalya, Kimiko Della Croce, Ivan G. Georgiev, Raymond B. Nagle, Harinder Garewal, Daniel D. Von Hoff, and Daruka Mahadevan Arizona Cancer Center; Southern Arizona VA Medical Center, Tucson, Arizona; TGen, Phoenix, Arizona; and National Institute for Medical Research, London, United Kingdom NSC348884, a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis in human cancer cells. W Qi, K Shakalya, A Stejskal, A Goldman, S Beeck, L Cooke and D Mahadevan Arizona Cancer Center, University of Arizona, Tucson, AZ, USA

NSC348884, a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis in human cancer cells.

W Qi, K Shakalya, A Stejskal, A Goldman, S Beeck, L Cooke and D Mahadevan Arizona Cancer Center, University of Arizona, Tucson, AZ, USA